Ormed Activated, Liposomal Delivery System TechnologyFor Tick-Borne and Chronic Infections
The Activated, Liposomal Delivery System Technology was developed by Professor Pierre-Henri Lagny of Izeste, France as part of his research on antimicrobial agents, and his quest to solve the problem of antibiotic resistance. According to research carried out by the East Coast Pharmaceutical Research Associates and the Department of Microbiology-Immunology of the University of Montreal Research Center, micro-dilutions of metal ions, even if they have no activity when used alone, multiply the efficacy of anti-infectious agents up to 1660% when added within a narrow, precise range. The efficacy is further increased by the use of liposomes. The process can be used with natural products with no contraindications or side-effects. The therapeutic benefits include 1) no more bacterial resistance, and 2) no chemical residues to discharge.
Dilutions of micrograms per milliliter are effective in vitro. But the active agent must be diluted in a 100 ml glass of water for oral consumption so only hundredths of millionths are actually ingested. At such dilutions, one assumes that no molecular contact is possible. Only the concept of chemical reactions as interactions of electromagnetic signals of molecules can explain this. This is NOT homeopathy. The activation comes from the precise proportion of electrolytes.
The three key elements of the Delivery System Technology are: Dilution, Dynamization and Dispersion
- Dilution of the base substances is in proportion to the electrolytes added to increase the potency. The dilution is equivalent to a dilution of 6X;
- Dynamization is brought about by precise calibration of the electrolyte minerals added to the ingredients; this results in activation of antimicrobial potential as well as efficiency in penetrating membranes;
- Dispersion is enhanced further by liposomal technology.
The Quest for the Conquest of Antibiotic Resistance To address the problem of antibiotic resistance, Professor Lagny proposed three types of solutions based on three concepts:
The concept of utilization of anti-infectious agents of natural origin
The concept of activation
The concept of dispersion
Natural Substances:
The efficacy of agents such as grapefruit seed extract, propolis, and essential oils is reported in a wide variety of publications, and were the subjects of Prof. Lagny's experimentation with a non-synthetic chemical approach to antimicrobial therapy.
Activation: Use of Metals as Antimicrobials
Besides essential oils, metals have historically been used as antimicrobials. It was also discovered that electrolytes enhance the effect of conventional antibiotics. This was found to be true apart from any antimicrobial properties the metals themselves may have. But Dr. Lagny felt that natural substances, which have more complex structures than the relatively simple chemical molecules used in antibiotic therapy, make it more difficult for bacteria to adapt.
The concept of activation was discovered during his research on agents that have the ability to inhibit bacterial enzymatic functions. Metal ions used in microdilution in a very precise amount, and only in this amount, can increase the potency of anti-infectious agents by 100%, 1000%, or more. This discovery has been patented. Metal salts such as lithium fluoride and Stannous fluoride were used in some of the tests, but they could arouse objections from the standpoint of safety. Sodium-free seawater, with its 83 elements containing all metals in trace amounts, was adopted for use to resolve the safety problem.
Enhanced Liposomal Delivery
The bilayer structure of liposomes is nearly identical to the bilayer construction of the cell membranes that surround each of the cells in the human body. This occurs because of the unique composition of phospholipids. The phosphate (source of "phospho" in phospholipid) head of phospholipids is hydrophilic — it loves water — whereas the fatty-acid tails (lipids) are hydrophobic — they hate water. When phospholipids find themselves in a water-based solution, the hydrophobic tails quickly move to distance themselves from the liquid just like oil separates from vinegar. So, as all the tails turn inward and all the heads turn toward the liquid, they form a double-layered membrane. Cells throughout the body are hungry for phospholipid materials to repair cell membranes and other cellular structures. In liposomal delivery, the cells can readily utilize the materials contained in the liposome allowing their contents to "leak out," i.e. be delivered into the cell's interior. The therapeutic value and greatly increased delivery of liposome-encapsulated drugs and nutrients has been scientifically confirmed many times. At present, liposomes are the most bioavailable oral way to deliver nutrients. Most liposomal dispersants use polyethylene glycol or propylene glycol. Dr. Lagny considers the plant cell wall-based dispersing agent in the production to be more compatible with living systems than synthetic sources. It makes essential oils and pungent substances such as grapefruit seed extract drinkable, using only 1/10 of the pure product, while preserving its efficiency.
Potent but Safe
Numerous doctors and pharmacists in France have attested to the potency of the supplements used in the Lyme and chronic infections protocol. Because of their low toxicity and safety, they cause no side effects with the exception of microbial die-off, which has been occasionally reported and easily mitigated.