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Highest strength Co Q10 in a convenient and absorbable softgel delivery systemWe are proud to announce our latest product improvement: our CoQ10 Power is now GMO-free & Soy-free. Our updated formulation incorporates GMO-free sunflower lipids and a new high quality annatto plant natural coloring to provide this extra-clean, high absorption product. This product upgrade is offered at the same very competitive price as before.
Coenzyme Q10 (CoQ10) is a compound found naturally in the energy-producing center of the cell known as the mitochondria. CoQ10 is involved in the making of an important molecule known as ATP. ATP serves as the cell's major energy source and drives a number of biological processes including muscle contraction and the production of protein. CoQ10 also works as an antioxidant.
Antioxidants are substances that scavenge free radicals, damaging compounds in the body that alter cell membranes, tamper with DNA, and even cause cell death. Free radicals occur naturally in the body, but environmental toxins (including ultraviolet light, radiation, cigarette smoking, and air pollution) can also increase the number of these damaging particles. Free radicals are believed to contribute to the aging process as well as the development of a number of health problems. Antioxidants such as CoQ10 can neutralize free radicals and may reduce or even help prevent some of the damage they cause.
CoQ10 boosts energy, enhances the immune system, and acts as an antioxidant. A growing body of research suggests that using Coenzyme Q10 supplements alone or in combination with other drug therapies and nutritional supplements supports the body s health in the following areas:
Promote Healthy Heart
Researchers believe that the beneficial effect of CoQ10 in the promoting a healthy heart is due to its ability to improve energy production in cells, inhibit blood clot formation, and act as an antioxidant. One important study, for example, found that people who received daily CoQ10 supplements within 3 days of a heart attack were significantly less likely to experience subsequent heart attacks and chest pain. In addition, these same patients were less likely to die of heart disease than those who did not receive the supplements.
Healthy Cholesterol Support
Levels of CoQ10 tend to be lower in people with high cholesterol compared to healthy individuals of the same age. In addition, certain cholesterol-lowering drugs called statins (such as atorvastatin, cerivastatin, lovastatin, pravastatin, simvastatin) appear to deplete natural levels of CoQ10 in the body. Taking CoQ10 supplements can correct the deficiency caused by statin medications without affecting the medication's positive effects on cholesterol levels.
Gum disease is a widespread problem that is associated with swelling, bleeding, pain, and redness of the gums. Studies have shown that people with gum disease tend to have low levels of CoQ10 in their gums. In a few studies involving small numbers of subjects, CoQ10 supplements caused faster healing and tissue repair. Additional studies are needed to evaluate the effectiveness of CoQ10 when used together with traditional therapy for periodontal disease.
Parkinson s Support
A multi-center study published in the Oct. 15, 2002 issue of the American Medical Association's Archives of Neurology, provide the first evidence that Coenzyme Q10 might slow the progression of the disease. Parkinson's disease is a degenerative disorder of the brain in which patients develop tremor, slowness of movement and stiffness of muscles. It affects approximately 1 percent of Americans over the age of 65. Although certain drugs, such as levodopa, can reduce the symptoms of Parkinson's disease, no treatment has been shown to slow the progressive deterioration in function.
Over the past several years, research by Shults, Haas and Beal showed that mitochondrial function is impaired in patients with Parkinson's disease and coenzyme Q10 levels are reduced in the mitochondria of parkinsonian patients. Beal and Shults studied coenzyme Q10 in an animal model of Parkinson's disease and found that it could protect the part of the brain affected by the disorder.
In the Parkinson Study Group national clinical trial, 80 Parkinson s patients who had early disease and did not yet need medications typically used to treat Parkinson's disease (such as levodopa), were randomly assigned to receive coenzyme Q10 four times a day at a dosage of 300, 600 or 1200 mg/day, or a placebo, also taken four times a day. Prior to beginning the study, the patients were evaluated with a medical history, physical exam, laboratory tests, and a battery of clinical assessments of Parkinson's disease. Participants were reevaluated with tests to assess the severity of the Parkinson's disease at regular intervals and followed until the time that they needed treatment with medications used to treat the symptoms of Parkinson's disease, or for a maximum of 16 months.
By the eighth month visit, the scores among the four groups had clearly separated and established a pattern of the groups taking the lowest and intermediate dosages (300 and 600 mg/day) being similar and lower than placebo and the scores for the group receiving the highest dosage (1200 mg/day) being substantially lower than the other groups. The lower score reflected less impairment and better function. This pattern persisted to the end of the study. The benefit was seen in assessment of mental function and mood, activities of daily living and motor skills.
If the drug had merely been ameliorating symptoms --while the disease continued unchecked to kill nerve cells -- the researchers would have expected the initial, first-month check-up to reveal improvement in the coenzyme Q10 groups. Since that was not the case, Shults hypothesized that the drug might have slowed the underlying progression of the disease over the 16-month period of the study.
As a dietary supplement, take one to three softgels per day or as directed by your healthcare professional.
Free of corn, soy, sugar, salt, preservatives, eggs, fish, crustacean fish, tree nuts, peanuts, wheat, gluten, casein, artificial flavors, artificial colors.
Frequently Asked Questions
1. Is CoQ10 Power gluten-free? Yes, it is.
2. What form of CoQ10 is in CoQ10 Power ? We use the ubiquinone form, the traditional form of CoQ10 that has been extensively studied in multiple research projects around the world, including Japan, Europe, Russia and the United States. We do, however, carry our Ubiquinol Super 200 for those who require the reduced form.
3. Is CoQ10 Power a natural-sourced product?Yes. We source only USP certified raw material and it is naturally fermented.
4. Does the softgel casing include titanium dioxide?
No. We use the highest quality annatto so we do not need to add titanium dioxide. Our formulating team sourced this much more expensive natural annatto because of research which questions the safety of titanium dioxide. Other brands may contain titanium dioxide without listing it on their labels if the amount is fairly low. However, CoQ10 Power is a very pure product and we did not want this ingredient to take away from this ultra-clean CoQ10.
If you are currently being treated with any of the following medications, you should not use CoQ10 without first talking to your healthcare provider:
Daunorubicin and Doxorubicin
- Coenzyme Q10 may help to reduce the toxic effects on the heart caused by daunorubicin and doxorubicin, two chemotherapy medications that are commonly used to treat a variety of cancers
Blood Pressure Medications
- In a study of individuals taking blood pressure medications (including diltiazem, metoprolol, enalapril, and nitrate), CoQ10 supplementation allowed the individuals to take lower dosages of these drugs. This suggests that CoQ10 may enhance the effectiveness of certain blood pressure medications, but more research is needed to verify these results.
- There have been reports that coenzyme Q10 may decrease the effectiveness of blood-thinning medications such as warfarin, leading to the need for increased doses. Therefore, given that this medication must be monitored very closely for maintenance of appropriate levels and steady blood thinning, CoQ10 should only be used with warfarin under careful supervision by the healthcare provider.
- CoQ10 supplementation may reduce the heart-related side effects of timolol drops, a beta-blocker medication used to treat glaucoma, without decreasing the effectiveness of the medication.
- Medications that can lower the levels of coenzyme Q10 in the body include statins for cholesterol (atorvastatin, cerivastatin, lovastatin, pravastatin, simvastatin), fibric acid derivatives for cholesterol (specifically, gemfibrozil), beta-blockers for high blood pressure (such as atenolol, labetolol, metoprolol, and propranolol), and tricyclic antidepressant medications (including amitriptyline, amoxapine, clomipramine, desipramine, doxepin, imipramine, nortriptyline, protriptyline, and trimipramine).
Aberg F, Appelkvist EL, Broijersen A, et al. Gemfibrozil-induced decrease in serum ubiquinone and alpha- and gamma-tocopherol levels in men with combined hyperlipidaemia.
Eur J Clin Invest. 1998;28:235-242.
Al-Hasso. Coenzyme Q10: a review. Hosp Pharm. 2001;36(1):51-66.
Alleva R, Scaraarmucci A, Mantera F, Bompandre S, Leoni L, Linarro GP. The protective role of ubiquinol 10 against formation of lipid hydroperoxdes in human seminal fluids. Mol Asp Med. 1997;18:221-228.
Baggio E, Gandini R, Plancher AC, Passeri M, Carmosino G. Italian multicenter study on the safety and efficacy of coenzyme Q10 as adjunctive therapy in heart failure. CoQ10 Drug Surveillance Investigators. Mol Aspects Med. 1994;15(Suppl):s287-294.
Chello M, Mastroroberto P, Romano R, et al. Protection by coenzyme Q10 from myocardial reperfusion injury during coronary artery bypass grafting. Ann Thorac Surg. 1994;58(5):1427-1432.
Chopra RK, Goldman R, Sinatra ST, Bhagavan HN. Relative bioavailability of coenzyme Q10 formulations in human subjects. Int J Vitam Nutr Res. 1998;68:109-113.
de Bustos F, Molina JA, Jimenez-Jimenz FJ, Garcia-Redondo A, Gomez-Escalonilla C, Porta-Etessam J, et al. Serum levels of coenzyme Q10 in patients with Alzheimer's disease. J Neural Transm. 2000;107(2):233-239.
Eriksson JG. The effects of coenzyme Q10 administration on metabolic control in patients with type 2 diabetes mellitus. Biofactors. 1999;9(2-4):315-318.
Folkers K, Langsjoen P, Nara Y, et al. Biochemical deficiencies of coenzyme Q10 in HIV infection and exploratory treatment. Biochem Biophys Res Commun. 1988;153:888-896.
Hanioka T, Tanaka M, Ojima M, Shizukuishi S, Folkers K. Effect of topical application of coenzyme Q10 on adult periodontitis. Mol Aspects Med. 1994;15 Suppl:s241-248.
Heck AM, DeWitt BA, Lukes AL. Potential interactions between alternative therapies and warfarin. Am J Health-System Pharm. 2000;57(13):1221-1227.